Thymosin-β4 (1-4)

What is Thymosin-β4 (1-4)?

Thymosin Beta-4 (1-4), also known as Ac-SDKP, is a peptide that aids in tissue repair by reducing fibrosis and inflammation. It helps to regulate collagen production and fibroblast activity, promoting more effective and balanced healing of tissues and reducing excessive scar formation.

Benefits

• Reduces Fibrosis (scar tissue formation)
• Promotes Wound Healing
• Decreases Inflammation
• Improves Tissue Regeneration

Mechanisms of Action

1. Fibroblast suppression: Thymosin-β4 (1-4) suppresses the activation and proliferation of fibroblasts, the cells responsible for producing collagen. By limiting fibroblast activity, it reduces excessive collagen accumulation, which helps to prevent fibrosis and scar tissue formation.

2. Regulation of Extracellular Matrix: Modulates the extracellular matrix (ECM) environment, influencing the balance between matrix degradation and synthesis. This regulation supports healthier tissue remodeling and prevents excessive ECM deposition.

3. Anti-inflammatory Effects: Thymosin-β4 (1-4) reduces the production of pro-inflammatory cytokines and chemokines. By decreasing inflammatory responses, it alleviates swelling and inflammation in damaged tissues, contributing to a more controlled and effective healing process.

4. Cell Migration and Proliferation Modulation: influences cell migration and proliferation, ensuring that these processes occur in a regulated manner. This helps to facilitate orderly tissue repair and reduces the risk of disorganized tissue formation.

5. Inhibition of TGF-β Activity: Thymosin-β4 (1-4) interferes with the activity of Transforming Growth Factor Beta (TGF-β), a key regulator of fibrosis. By inhibiting TGF-β signaling, it reduces the fibrotic response and supports a more balanced tissue repair process.

Dosage

Take 1-2 capsules daily or as directed by a physician.